Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355257 | 1.00 | SLC1A3 (0.32) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10119429 | 0.89 | GRIK1 (0.36) | — | |
| SCHEMBL28626659 | 0.89 | GRIK1 (0.36) | — | |
| SCHEMBL4449229 | 0.86 | — | — | |
| SCHEMBL2997282 | 0.81 | MMP1 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11141173 | 0.81 | SLC1A3 (0.30) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2997284 | 0.81 | MMP1 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11137107 | 0.78 | — | — | |
| SCHEMBL8101229 | 0.77 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2035309 | 0.77 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2189442-B1 | Process and intermediates for the preparation of aliskiren | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2014-10-01 | — | — | EP | disclosed |
| EP-2189442-A1 | Process and intermediates for the preparation of aliskiren | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2010-05-26 | — | — | EP | disclosed |