SCHEMBL10119904

SCHEMBL10119904

C[C@H]1C2CC(C[C@@H]2NC(=O)OC(C)(C)C)[C@@H]1C(=O)OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.43
CTSL P07711 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SYK P43405 1/20 0.41
PDE4B Q07343 1/20 0.40
KDM1A O60341 2/20 0.40
MAOB P27338 1/20 0.40
FABP7 O15540 1/20 0.39
FABP5 Q01469 1/20 0.39
CYP3A4 P08684 2/20 0.37
TSHR P16473 2/20 0.37
KLK7 P49862 1/20 0.37
KLK5 Q9Y337 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13198696 1.00 CPB1 (0.43) CPB1CTSLKMT2AL3MBTL1SYK
SCHEMBL10119907 0.91 FABP7 (0.44) CPB1CTSLKMT2AL3MBTL1SYK
SCHEMBL13198690 0.91 FABP7 (0.44) CPB1CTSLKMT2AL3MBTL1SYK
SCHEMBL10119909 0.90 CPB1 (0.48) CPB1CTSLKMT2AL3MBTL1SYK
SCHEMBL10119906 0.90 CPB1 (0.48) CPB1CTSLKMT2AL3MBTL1SYK
SCHEMBL13198694 0.90 CPB1 (0.48) CPB1CTSLKMT2AL3MBTL1SYK
SCHEMBL22617362 0.81 CPB1 (0.54) CPB1CTSLKMT2AL3MBTL1SYK
SCHEMBL14827596 0.81 FABP7 (0.48) KMT2AL3MBTL1FABP7FABP5TSHR
SCHEMBL8691884 0.78 SYK (0.50) CPB1CTSLKMT2AL3MBTL1SYK
SCHEMBL8691889 0.78 SYK (0.50) CPB1CTSLKMT2AL3MBTL1SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130081999-A1 Bridged Macrocyclic Module Compositions WHITEFORD JEFFERY A (US) 2013-04-04 US disclosed
US-8110679-B2 Nanofilm and membrane compositions COVALENT PARTNERS LLC (US) 2012-02-07 US disclosed
US-7595368-B2 Nanofilm compositions with polymeric components COVALENT PARTNERS, LLC (US) 2009-09-29 US disclosed
US-20090114596-A1 NANOFILM AND MEMBRANE COMPOSITIONS COVALENT PARTNERS LLC 2009-05-07 US disclosed
US-7432371-B2 Nanofilm and membrane compositions COVALENT PARTNERS, LLC (US) 2008-10-07 US disclosed
US-7368564-B2 Bridged macrocyclic module compositions COVALENT PARTNERS, LLC (US) 2008-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130081999-A1 Bridged Macrocyclic Module Compositions SBDS, NCL, INTS6 CPB1 1531/4885CTSL 1353/4885KMT2A 3432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.