SCHEMBL10119915

SCHEMBL10119915

COC(=O)[C@@H]1C2CC([C@H]1C)[C@@H](C)[C@@H]2C(=O)OCc1ccc(OC)cc1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FABP7 O15540 1/20 0.51
▸ FABP5 Q01469 1/20 0.51
▸ ALDH1A1 P00352 5/20 0.51
▸ HTT P42858 4/20 0.51
▸ HPGD P15428 2/20 0.51
▸ GLA P06280 1/20 0.51
▸ MAPT P10636 1/20 0.42
▸ MIF P14174 1/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ ATM Q13315 1/20 0.40
▸ PKM P14618 1/20 0.40
▸ KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13688299 1.00 FABP7 (0.51) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL10119916 1.00 FABP7 (0.51) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL6737480 1.00 FABP7 (0.51) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL6737702 1.00 FABP7 (0.51) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL6736507 0.96 ALDH1A1 (0.50) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL10119919 0.96 ALDH1A1 (0.50) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL14827601 0.92 FABP7 (0.53) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL14827600 0.92 FABP7 (0.53) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL6737709 0.92 FABP7 (0.55) FABP7FABP5ALDH1A1HTTHPGD
SCHEMBL10119917 0.92 FABP7 (0.55) FABP7FABP5ALDH1A1HTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110679-B2 Nanofilm and membrane compositions COVALENT PARTNERS LLC (US) 2012-02-07 — — US disclosed
US-7767810-B2 Macrocyclic modules comprising linked cyclic synthon units for use in the formation of selectively permeable membranes COVALENT PARTNERS, LLC (US) 2010-08-03 — — US disclosed
US-20100152438-A1 AMPHIPHILIC MOLECULAR MODULES AND CONSTRUCTS BASED THEREON COVALENT PARTNERS LLC 2010-06-17 — — US disclosed
US-7563890-B2 Amphiphilic molecular modules and constructs based thereon COVALENT PARTNERS, LLC (US) 2009-07-21 — — US disclosed
US-20090114596-A1 NANOFILM AND MEMBRANE COMPOSITIONS COVALENT PARTNERS LLC 2009-05-07 — — US disclosed
US-7432371-B2 Nanofilm and membrane compositions COVALENT PARTNERS, LLC (US) 2008-10-07 — — US disclosed
US-7368564-B2 Bridged macrocyclic module compositions COVALENT PARTNERS, LLC (US) 2008-05-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152438-A1 AMPHIPHILIC MOLECULAR MODULES AND CONSTRUCTS BASED THEREON ANXA6, THEM6, ANXA5 FABP7 90/4885FABP5 126/4885ALDH1A1 4330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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