Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15179447 | 0.92 | KDM4E (0.53) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL17772010 | 0.91 | GAA (0.53) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL10048672 | 0.88 | GAA (0.52) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL10049161 | 0.87 | GAA (0.52) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL10049160 | 0.86 | GAA (0.52) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL10049172 | 0.86 | GAA (0.52) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL10120323 | 0.85 | GAA (0.49) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL10048728 | 0.85 | NCF1 (0.46) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL14963805 | 0.85 | GAA (0.49) | GAAMAPTKDM4EALDH1A1CASP1 | |
| SCHEMBL10120322 | 0.84 | GAA (0.46) | GAAMAPTKDM4EALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018662-A2 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |