SCHEMBL1012023

SCHEMBL1012023

NC(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.63
NPSR1 Q6W5P4 1/20 0.61
NAALAD2 Q9Y3Q0 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
ACE P12821 2/20 0.56
CPA1 P15085 2/20 0.56
ACE2 Q9BYF1 2/20 0.56
CA2 P00918 2/20 0.56
CA1 P00915 1/20 0.56
POLB P06746 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
FPR2 P25090 4/20 0.55
PTPN1 P18031 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012022 1.00 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL1012053 1.00 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
Hydrochloric Acid SCHEMBL1262435 0.98 MME (0.61) MMENPSR1NAALAD2L3MBTL1ACE
Ammonia Solution, Strong SCHEMBL10824808 0.98 MME (0.61) MMENPSR1NAALAD2L3MBTL1ACE
Ammonia Solution, Strong SCHEMBL10824805 0.98 MME (0.61) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL6853867 0.89 HPGDS (0.56) MMEPOLBSMN1; SMN2
SCHEMBL26527726 0.86 NAALAD2 (0.61) MMENPSR1NAALAD2L3MBTL1FPR2
SCHEMBL8072837 0.86 MME (0.60) MMEACECPA1ACE2
SCHEMBL3829705 0.86 FOLH1 (0.61) MMENAALAD2L3MBTL1ACECPA1
SCHEMBL1498340 0.86 MME (0.59) MMENPSR1NAALAD2L3MBTL1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6953677-B2 Recombinant L-N-carbamoylase from Arthrobacter aurescens and method of producing L-amino acids therewith DEGUSSA AG (DE) 2005-10-11 US claimed
EP-1001764-A4 HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS MERCK & CO INC (US) 2005-08-24 EP claimed
CN-1164736-C Method for preparing series D-alpha-amino acid by using Burkholderia cepacia JS-02 �Ͼ���ҵ��ѧ 2004-09-01 CN claimed
CN-1431295-A Method for preparing series D-a-amino acids by using Burkholderia cepacia JS-02 NANJING INDUSTRY UNIV (CN) 2003-07-23 CN claimed
EP-1209234-A1 STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2002-05-29 EP claimed
JP-2002512625-A 2002-04-23 JP claimed
EP-1001764-A1 HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS Merck & Co., Inc. (a New Jersey corp.) (US) 2000-05-24 EP claimed
WO-1999064395-A1 HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS MERCK & CO., INC. (US) 1999-12-16 WO claimed
WO-1998053814-A1 HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS MERCK & CO., INC. (US) 1998-12-03 WO claimed
CN-1100426-A Lysosomal enzyme-cleavable antitumor drug conjugates BRISTOL MYERS SQUIBB CO (US) 1995-03-22 CN claimed
EP-0159866-B1 PROCESS FOR PRODUCTION OF L-AMINO ACIDS DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-04-03 EP claimed
EP-0159866-A2 Process for production of L-amino acids DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-10-30 EP claimed
JP-60011457-A None JP disclosed
JP-1139560-A None JP disclosed
JP-61122261-A None JP disclosed
JP-61148156-A None JP disclosed
US-4252812-A TRANQUILIZERS PFIZER INC. (US) 1981-02-24 US disclosed
US-4237227-A ENZYMATIC HYDROLYSIS OF A HYDANTOIN KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1980-12-02 US disclosed
US-4224329-A TRANQUILIZERS PFIZER INC. (US) 1980-09-23 US disclosed
JP-S06363395-A 0001-01-01 JP disclosed