SCHEMBL1012053

SCHEMBL1012053

NC(=O)N[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.63
NPSR1 Q6W5P4 1/20 0.61
NAALAD2 Q9Y3Q0 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
ACE P12821 2/20 0.56
CPA1 P15085 2/20 0.56
ACE2 Q9BYF1 2/20 0.56
CA2 P00918 2/20 0.56
CA1 P00915 1/20 0.56
POLB P06746 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
FPR2 P25090 4/20 0.55
PTPN1 P18031 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012022 1.00 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL1012023 1.00 MME (0.63) MMENPSR1NAALAD2L3MBTL1ACE
Hydrochloric Acid SCHEMBL1262435 0.98 MME (0.61) MMENPSR1NAALAD2L3MBTL1ACE
Ammonia Solution, Strong SCHEMBL10824808 0.98 MME (0.61) MMENPSR1NAALAD2L3MBTL1ACE
Ammonia Solution, Strong SCHEMBL10824805 0.98 MME (0.61) MMENPSR1NAALAD2L3MBTL1ACE
SCHEMBL6853867 0.89 HPGDS (0.56) MMEPOLBSMN1; SMN2
SCHEMBL26527726 0.86 NAALAD2 (0.61) MMENPSR1NAALAD2L3MBTL1FPR2
SCHEMBL8072837 0.86 MME (0.60) MMEACECPA1ACE2
SCHEMBL3829705 0.86 FOLH1 (0.61) MMENAALAD2L3MBTL1ACECPA1
SCHEMBL1498340 0.86 MME (0.59) MMENPSR1NAALAD2L3MBTL1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709235-B2 5-Substituted hydantoin racemase, DNA encoding the same, recombinant DNA, transformed cell, and process for production of optically active N-carbamylamino acid or optically active amino acid KANEKA CORPORATION (JP) 2010-05-04 US claimed
US-20080261268-A1 5-Substituted Hydantoin Racemase, Dna Encoding the Same, Recombinant Dna, Transformed Cell, and Process for Production of Optically Active N-Carbamylamino Acid or Optically Active Amino Acid KANEKA CORPORATION (JP) 2008-10-23 US claimed
EP-1852510-A1 5-SUBSTITUTED HYDANTOIN RACEMASE, DNA ENCODING THE SAME, RECOMBINANT DNA, TRANSFORMED CELL, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE N-CARBAMYLAMINO ACID OR OPTICALLY ACTIVE AMINO ACID Kaneka Corporation (JP) 2007-11-07 EP claimed
CN-1376202-A Stereostructure of decarbamylase and use thereof KANEGAFUCHI CHEMICAL IND (JP) 2002-10-23 CN claimed
EP-1209234-A1 STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2002-05-29 EP claimed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
CN-115772513-A D-carbamyl hydrolase mutant, gene, expression vector and application thereof 江南大学 2023-03-10 CN disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
CN-115232130-A APN and AKT double-target-point inhibitor and preparation method and application thereof 山东大学 2022-10-25 CN disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
CN-111454933-B D-carbamoyl hydrolase mutant and application thereof in synthesis of D-aromatic amino acid 江南大学 2022-08-16 CN disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-4418146-A CBS 303.80 OR CBS 363.50 THERMOPHILIC, NON-SPORULATING STRAINS BASF AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
EP-0046186-A2 Method of preparing D-N-carbamoyl-alpha-amino acids, and microorganisms therefor BASF Aktiengesellschaft (DE) 1982-02-24 EP disclosed
US-4312948-A AGROBACTERIUM CULTURE SNAMPROGETTI S.P.A. (IT) 1982-01-26 US disclosed
US-4277404-A INTERMEDIATES FOR TRANQUILIZERS PFIZER INC. (US) 1981-07-07 US disclosed
US-4267331-A REDUCTIVE ALKYLATION OF A 5-PHENYL-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO/4,3-B/INDOLE WITH A REDUCING AGENT AND A 2-HYDROXY-5- OR 6-PHENYLFURAN OR -PYRAN PFIZER INC. (US) 1981-05-12 US disclosed
US-4252812-A TRANQUILIZERS PFIZER INC. (US) 1981-02-24 US disclosed
US-4237227-A ENZYMATIC HYDROLYSIS OF A HYDANTOIN KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1980-12-02 US disclosed
US-4224329-A TRANQUILIZERS PFIZER INC. (US) 1980-09-23 US disclosed