Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765808 | 0.92 | BDKRB1 (0.48) | BDKRB1CXCR4CNR1METCARM1 | |
| SCHEMBL764462 | 0.87 | BDKRB1 (0.40) | BDKRB1CXCR4CNR1 | |
| SCHEMBL10121140 | 0.87 | BDKRB1 (0.41) | BDKRB1CXCR4CNR1METL3MBTL1 | |
| SCHEMBL764468 | 0.85 | BDKRB1 (0.48) | BDKRB1CXCR4CNR1METCARM1 | |
| SCHEMBL12239074 | 0.84 | BDKRB1 (0.49) | BDKRB1CNR1METCARM1PRMT6 | |
| SCHEMBL765831 | 0.82 | BDKRB1 (0.51) | BDKRB1CXCR4CNR1METPYGL | |
| SCHEMBL765522 | 0.82 | BDKRB1 (0.50) | BDKRB1CXCR4CNR1METCARM1 | |
| Hydrochloric Acid SCHEMBL2546804 | 0.81 | BDKRB1 (0.49) | BDKRB1CXCR4CNR1METCARM1 | |
| SCHEMBL10121221 | 0.79 | BDKRB1 (0.47) | BDKRB1CXCR4CNR1MET | |
| SCHEMBL10121264 | 0.79 | BDKRB1 (0.49) | BDKRB1CXCR4CNR1METAP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |