Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121264 | 0.92 | BDKRB1 (0.49) | BDKRB1PTGER4CNR1MAPK14CYP3A4 | |
| SCHEMBL764462 | 0.92 | BDKRB1 (0.40) | BDKRB1PTGER4CNR1CXCR4 | |
| SCHEMBL10121183 | 0.87 | BDKRB1 (0.41) | BDKRB1CNR1L3MBTL1CXCR4MET | |
| SCHEMBL765524 | 0.87 | BDKRB1 (0.51) | BDKRB1PTGER4CNR1MAPK14CYP3A4 | |
| SCHEMBL765612 | 0.86 | BDKRB1 (0.45) | BDKRB1PTGER4CNR1MAPK14CYP3A4 | |
| SCHEMBL765522 | 0.85 | BDKRB1 (0.50) | BDKRB1PTGER4CNR1CXCR4MET | |
| Hydrochloric Acid SCHEMBL2546804 | 0.84 | BDKRB1 (0.49) | BDKRB1PTGER4CNR1CXCR4MET | |
| SCHEMBL10121221 | 0.83 | BDKRB1 (0.47) | BDKRB1PTGER4CNR1CXCR4MET | |
| SCHEMBL12239072 | 0.83 | BDKRB1 (0.51) | BDKRB1CNR1MAPK14CYP3A4HTT | |
| SCHEMBL2547691 | 0.83 | BDKRB1 (0.53) | BDKRB1CNR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |