Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121221 | 0.92 | BDKRB1 (0.47) | BDKRB1CNR1PTGDR2LMNASCN9A | |
| SCHEMBL10121140 | 0.92 | BDKRB1 (0.41) | BDKRB1CNR1CXCR4PTGER4 | |
| SCHEMBL10121183 | 0.87 | BDKRB1 (0.41) | BDKRB1CNR1CXCR4 | |
| SCHEMBL12239073 | 0.85 | BDKRB1 (0.47) | BDKRB1CNR1WDR5 | |
| SCHEMBL10121264 | 0.84 | BDKRB1 (0.49) | BDKRB1CNR1CXCR4PTGER4 | |
| SCHEMBL764420 | 0.81 | BDKRB1 (0.48) | BDKRB1CNR1CXCR4PTGER4 | |
| SCHEMBL765524 | 0.80 | BDKRB1 (0.51) | BDKRB1CNR1SCN9ACXCR4PTGER4 | |
| SCHEMBL12239072 | 0.80 | BDKRB1 (0.51) | BDKRB1CNR1CXCR4 | |
| SCHEMBL2547691 | 0.80 | BDKRB1 (0.53) | BDKRB1CNR1 | |
| SCHEMBL764501 | 0.80 | BDKRB1 (0.49) | BDKRB1CNR1PTGDR2LMNALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |