Sugi Predict

Sugi Predict / Compounds / SCHEMBL10121689

SCHEMBL10121689

SCHEMBL10121689

CCN(CC)CCCS(=O)(=O)N[C@H](CCc1ccccc1)c1nc(CNC(=O)NC(C)C)n[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 1/20 0.61
▸ LMNA P02545 1/20 0.38
▸ GAA P10253 1/20 0.37
▸ CCR4 P51679 2/20 0.35
▸ EPHX2 P34913 6/20 0.34
▸ SCN1A P35498 1/20 0.34
▸ SCN2A Q99250 1/20 0.34
▸ SCN3A Q9NY46 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ HDAC3 O15379 1/20 0.33
▸ HDAC4 P56524 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC7 Q8WUI4 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ HDAC10 Q969S8 1/20 0.33
▸ HDAC11 Q96DB2 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ HDAC9 Q9UKV0 1/20 0.33
▸ HDAC5 Q9UQL6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1709655 0.94 GHSR (0.60) GHSRLMNAGAACCR4EPHX2
SCHEMBL10121950 0.93 GHSR (0.64) GHSRLMNAGAACCR4EPHX2
SCHEMBL10122211 0.91 GHSR (0.60) GHSRLMNAGAACCR4SCN1A
SCHEMBL10121683 0.90 GHSR (0.63) GHSRLMNAGAACCR4SCN1A
SCHEMBL10122103 0.90 GHSR (0.65) GHSRLMNAGAACCR4SCN1A
SCHEMBL10121849 0.89 GHSR (0.62) GHSRLMNAGAACCR4SCN1A
SCHEMBL10121676 0.89 GHSR (0.64) GHSRLMNAGAACCR4SCN1A
SCHEMBL10121682 0.89 GHSR (0.69) GHSRLMNAGAACCR4SCN1A
SCHEMBL1709556 0.89 GHSR (0.61) GHSRLMNAGAACCR4SCN1A
SCHEMBL1709677 0.89 GHSR (0.63) GHSRLMNAGAACCR4SCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120088747-A1 SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF ELIXIR PHARMACEUTICALS, INC. 2012-04-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088747-A1 SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF GHSR, GHRHR, STS GHSR 1/4885LMNA 3245/4885GAA 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.