Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 10/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 9/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 9/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709552 | 0.88 | GHSR (0.59) | GHSRGAAALDH1A1TSHRKMT2A | |
| SCHEMBL1709675 | 0.88 | GHSR (0.59) | GHSRGAAALDH1A1TSHRKMT2A | |
| SCHEMBL10122121 | 0.88 | GHSR (0.54) | GHSRGAACACNA1ICACNA1GCACNA1H | |
| SCHEMBL1709663 | 0.87 | GHSR (0.58) | GHSRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL10121679 | 0.87 | GHSR (0.57) | GHSRGAAHPGDTSHRKMT2A | |
| SCHEMBL10121678 | 0.86 | GHSR (0.59) | GHSRGAAALDH1A1TSHRSCN1A | |
| SCHEMBL1709620 | 0.85 | GHSR (0.56) | GHSRGAAMEN1KMT2A | |
| SCHEMBL10122103 | 0.85 | GHSR (0.65) | GHSRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1709717 | 0.85 | GHSR (0.57) | GHSRGAAHPGDTSHRKMT2A | |
| SCHEMBL10122192 | 0.85 | GHSR (0.57) | GHSRGAAALDH1A1TSHRSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088747-A1 | SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF | ELIXIR PHARMACEUTICALS, INC. | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088747-A1 | SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF | GHSR, GHRHR, STS | GHSR 1/4885GAA 55/4885CACNA1I 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.