Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 18/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121648 | 0.97 | GHSR (0.43) | GHSRCCR5HDAC1HDAC6 | |
| SCHEMBL10122085 | 0.89 | GHSR (0.42) | GHSRCCR5HDAC1HDAC6 | |
| SCHEMBL10122096 | 0.89 | GHSR (0.47) | GHSRCCR5HDAC1HDAC6 | |
| SCHEMBL10122225 | 0.86 | GHSR (0.44) | GHSRCCR5HDAC1HDAC6 | |
| SCHEMBL10121971 | 0.85 | GHSR (0.44) | GHSRCCR5HDAC1HDAC6 | |
| SCHEMBL10121725 | 0.85 | GHSR (0.49) | GHSRHDAC1HDAC6 | |
| SCHEMBL1709692 | 0.85 | GHSR (0.48) | GHSRHDAC1HDAC6 | |
| SCHEMBL1709627 | 0.83 | GHSR (0.46) | GHSRCCR5HDAC1HDAC6 | |
| SCHEMBL1709720 | 0.83 | GHSR (0.52) | GHSRHDAC1HDAC6 | |
| SCHEMBL1709673 | 0.83 | GHSR (0.52) | GHSRHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088747-A1 | SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF | ELIXIR PHARMACEUTICALS, INC. | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088747-A1 | SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF | GHSR, GHRHR, STS | GHSR 1/4885CCR5 4058/4885HDAC1 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.