SCHEMBL10122333

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10122377	0.96	ALOX5 (0.45)	ALOX5GGPS1AHRPTGES2ALDH1A1
	SCHEMBL10122355	0.93	ALOX5 (0.46)	ALOX5GGPS1AHRPTGES2ALDH1A1
	SCHEMBL10122556	0.92	ALOX5 (0.42)	ALOX5GGPS1AHRPTGES2ALDH1A1
	SCHEMBL10122630	0.91	ALOX5 (0.44)	ALOX5GGPS1AHRPTGES2ALDH1A1
	SCHEMBL10122372	0.91	ALOX5 (0.43)	ALOX5GGPS1AHRALDH1A1HSD17B10
	SCHEMBL10122589	0.91	ALOX5 (0.43)	ALOX5GGPS1AHRPTGES2ALDH1A1
	SCHEMBL10122365	0.90	ALOX5 (0.42)	ALOX5GGPS1AHRPTGES2ALDH1A1
	SCHEMBL10122329	0.90	ALOX5 (0.45)	ALOX5AHRALDH1A1HSD17B10MAPT
	SCHEMBL10122483	0.89	ALOX5 (0.47)	ALOX5GGPS1AHRPTGES2ALDH1A1
	SCHEMBL20127666	0.89	ALOX5 (0.56)	ALOX5GGPS1AHRPTGES2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.