SCHEMBL10122752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9106387	0.90	MAOB (0.48)	MAOBMAOAABCG2PAX8CYP1A2
	SCHEMBL19786609	0.89	GABRP (0.49)	MAOBMAOAGABRPGABRDGABRA1
	SCHEMBL18803774	0.88	MAOB (0.44)	MAOBABCG2PAX8CYP1A2CYP1A1
	SCHEMBL16543094	0.86	ABCG2 (0.53)	ABCG2PAX8CYP1A2CYP1A1FYN
	SCHEMBL10122748	0.85	TDP1 (0.47)	ABCG2PAX8CYP1A2CYP1A1FYN
	SCHEMBL31191964	0.85	TDP1 (0.47)	ABCG2PAX8CYP1A2CYP1A1FYN
	SCHEMBL10122711	0.84	ABCG2 (0.44)	ABCG2PAX8CYP1A2CYP1A1FYN
	SCHEMBL23692995	0.83	CYP1A2 (0.50)	ABCG2PAX8CYP1A2CYP1A1FYN
	SCHEMBL16067564	0.83	MAOB (0.47)	MAOBMAOAABCG2CYP1A2CYP1A1
	SCHEMBL21190659	0.82	AHR (0.45)	MAOAABCG2PAX8CYP1A2CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.