Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27432182 | 0.88 | NISCH (0.40) | NISCHTP53METAP2NPC1RAB9A | |
| SCHEMBL1702558 | 0.74 | TP53 (0.56) | NISCHTP53METAP2EGFRTAAR1 | |
| SCHEMBL2776957 | 0.74 | TP53 (0.56) | NISCHTP53METAP2EGFRTAAR1 | |
| SCHEMBL24181347 | 0.72 | TRPA1 (0.37) | TAAR1CYP2A6 | |
| SCHEMBL23793237 | 0.71 | DHODH (0.42) | POLBTAAR1MAPTMEN1KMT2A | |
| SCHEMBL13530917 | 0.71 | NISCH (0.40) | NISCHTP53METAP2NPC1RAB9A | |
| SCHEMBL36295 | 0.71 | TP53 (0.67) | TP53TAAR1SMN1; SMN2ALDH1A1CYP2A6 | |
| SCHEMBL24230559 | 0.70 | NISCH (0.39) | NISCHTP53METAP2NPC1RAB9A | |
| SCHEMBL24181382 | 0.69 | MMP12 (0.40) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4321920 | 0.69 | NISCH (0.44) | NISCHTP53METAP2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119314-B1 | Imaging devices comprising structured organic films | XEROX CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |