Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14654319 | 0.90 | TDP1 (0.47) | TDP1ALDH1A1L3MBTL1TSHRKDM4E | |
| SCHEMBL16519352 | 0.85 | TDP1 (0.41) | TDP1ALDH1A1L3MBTL1TSHRKDM4E | |
| SCHEMBL12280905 | 0.85 | TDP1 (0.46) | TDP1ALDH1A1L3MBTL1TSHRKDM4E | |
| SCHEMBL14654314 | 0.84 | TDP1 (0.57) | TDP1ALDH1A1L3MBTL1TSHRKDM4E | |
| SCHEMBL15267532 | 0.81 | TDP1 (0.39) | TDP1ALDH1A1L3MBTL1TSHRKDM4E | |
| SCHEMBL10123080 | 0.81 | LMNA (0.48) | TDP1ALDH1A1L3MBTL1MAPTHSP90AA1 | |
| SCHEMBL18973645 | 0.81 | TDP1 (0.64) | TDP1ALDH1A1L3MBTL1TSHRKDM4E | |
| SCHEMBL15267530 | 0.81 | TDP1 (0.43) | TDP1ALDH1A1L3MBTL1TSHRKDM4E | |
| SCHEMBL12871785 | 0.81 | LMNA (0.48) | TDP1ALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL16519353 | 0.80 | TDP1 (0.65) | TDP1ALDH1A1L3MBTL1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9846168-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2017-12-19 | — | — | US | disclosed |
| US-9846168-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2016-10-20 | — | — | US | disclosed |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2016-10-20 | — | — | US | disclosed |
| US-9372181-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2016-06-21 | — | — | US | disclosed |
| US-9372181-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2016-06-21 | — | — | US | disclosed |
| US-20140363824-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-20140363824-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8785208-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785208-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | Life Technologies Corporation (US) | 2012-01-12 | — | — | US | disclosed |
| US-20100196922-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | Life Technologies Corporation (US) | 2010-08-05 | — | — | US | disclosed |
| US-20090029389-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | INVITROGEN CORPORATION (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | TDP1 4582/4885ALDH1A1 3754/4885L3MBTL1 3350/4885 |
| US-20100196922-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | SARAF, STIM1, ORAI1 | TDP1 4582/4885ALDH1A1 3754/4885L3MBTL1 3350/4885 |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | TDP1 4582/4885ALDH1A1 3754/4885L3MBTL1 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.