Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MMP10 | P09238 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123095 | 0.94 | MAOB (0.34) | MAOBMAPTLMNATP53NAMPT | |
| SCHEMBL15887243 | 0.91 | TDP1 (0.33) | MAOBMAPTLMNATP53NAMPT | |
| SCHEMBL10123099 | 0.75 | MAPT (0.36) | MAPTLMNATP53NAMPTPOLB | |
| SCHEMBL15267530 | 0.70 | TDP1 (0.43) | MAPTLMNAPOLBKMT2A | |
| SCHEMBL14654319 | 0.70 | TDP1 (0.47) | MAPTLMNAPOLBKMT2AGAA | |
| SCHEMBL10123077 | 0.68 | TDP1 (0.40) | MAPT | |
| SCHEMBL10123102 | 0.68 | SCP2 (0.38) | MAPTLMNATP53NAMPTPOLB | |
| SCHEMBL10264705 | 0.67 | APP (0.44) | MAOBMAPTLMNATP53GAA | |
| SCHEMBL15887263 | 0.66 | SCP2 (0.36) | MAPTLMNATP53NAMPTPOLB | |
| SCHEMBL12280905 | 0.66 | TDP1 (0.46) | MAPTLMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9846168-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2017-12-19 | — | — | US | disclosed |
| US-9846168-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2016-10-20 | — | — | US | disclosed |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2016-10-20 | — | — | US | disclosed |
| US-9372181-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2016-06-21 | — | — | US | disclosed |
| US-9372181-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2016-06-21 | — | — | US | disclosed |
| US-20140363824-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-20140363824-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8785208-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785208-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | Life Technologies Corporation (US) | 2012-01-12 | — | — | US | disclosed |
| US-20100196922-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | Life Technologies Corporation (US) | 2010-08-05 | — | — | US | disclosed |
| US-20090029389-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | INVITROGEN CORPORATION (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | MAOB 4603/4885MAPT 1199/4885LMNA 2985/4885 |
| US-20100196922-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | SARAF, STIM1, ORAI1 | MAOB 4603/4885MAPT 1199/4885LMNA 2985/4885 |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | MAOB 4603/4885MAPT 1199/4885LMNA 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.