Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | HTR6 | P50406 | 8/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123299 | 0.93 | THRB (0.55) | THRBTP53HTR6RXFP1SMN1; SMN2 | |
| SCHEMBL10123256 | 0.85 | THRB (0.64) | THRBTP53HTR6RXFP1KDM4E | |
| SCHEMBL10123316 | 0.85 | THRB (0.63) | THRBTP53HTR6RXFP1SMN1; SMN2 | |
| SCHEMBL10123313 | 0.85 | THRB (0.63) | THRBTP53HTR6RXFP1SMN1; SMN2 | |
| SCHEMBL667284 | 0.85 | THRB (0.79) | THRBTP53HTR6RXFP1SMN1; SMN2 | |
| SCHEMBL8029045 | 0.84 | KDM4E (0.61) | THRBTP53HTR6RXFP1KDM4E | |
| SCHEMBL10123311 | 0.83 | THRB (0.61) | THRBTP53HTR6RXFP1SMN1; SMN2 | |
| SCHEMBL10123317 | 0.83 | THRB (0.61) | THRBTP53HTR6RXFP1KDM4E | |
| SCHEMBL13573198 | 0.82 | THRB (0.60) | THRBTP53HTR6RXFP1SMN1; SMN2 | |
| SCHEMBL10123264 | 0.81 | THRB (0.58) | THRBTP53HTR6RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046282-A1 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046282-A1 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | FDFT1, COASY, KAT5 | THRB 2096/4885TP53 4676/4885HTR6 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.