Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.53 |
| ▸ | DCK | P27707 | 13/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | POLG | P54098 | 1/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10109720 | 0.84 | ALB (0.41) | ALBNR1I2PDE4DADCY5 | |
| SCHEMBL10098889 | 0.82 | ALB (0.47) | ALBDCKPOLG | |
| SCHEMBL307573 | 0.82 | ALB (0.47) | ALBDCKPOLG | |
| SCHEMBL4930216 | 0.80 | ALB (0.45) | ALBDCKPOLG | |
| SCHEMBL599406 | 0.79 | ALB (0.56) | ALBDCKPOLG | |
| SCHEMBL599407 | 0.79 | ALB (0.56) | ALBDCKPOLG | |
| SCHEMBL4437868 | 0.78 | ALB (0.44) | ALBDCKPOLGADCY5 | |
| SCHEMBL28741406 | 0.78 | ALB (0.37) | ALBNR1I2PDE4DADCY5 | |
| SCHEMBL14354922 | 0.77 | POLG (0.62) | ALBPOLG | |
| SCHEMBL15046170 | 0.77 | LMNA (0.50) | ALBNR1I2PDE4DPOLGADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160158266-A1 | 2' FLUORONUCLEOSIDES | EMORY UNIVERSITY | 2016-06-09 | — | — | US | disclosed |
| US-9180138-B2 | 2′-fluoronucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-20130157971-A1 | 2'-FLUORONUCLEOSIDES | SCHINAZI RAYMOND F (US) | 2013-06-20 | — | — | US | disclosed |
| US-8168583-B2 | 2-fluoronucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20100173863-A1 | 2-Fluoronucleosides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-07-08 | — | — | US | disclosed |
| US-7307065-B2 | 2′-Fluoronucleosides | EMORY UNIVERSITY (US) | 2007-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173863-A1 | 2-Fluoronucleosides | PNP, BCL3, NPC1 | ALB 2753/4885DCK 57/4885NR1I2 2587/4885 |
| US-20160158266-A1 | 2' FLUORONUCLEOSIDES | PNP, BCL3, NPC1 | ALB 2635/4885DCK 60/4885NR1I2 2595/4885 |
| US-20130157971-A1 | 2'-FLUORONUCLEOSIDES | PNP, BCL3, FUBP3 | ALB 2527/4885DCK 75/4885NR1I2 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.