Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 16/20 | 0.56 |
| ▸ | CA1 | P00915 | 14/20 | 0.56 |
| ▸ | CA9 | Q16790 | 7/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422371 | 0.94 | GAA (0.69) | LMNAGAAMAPTHTTCA2 | |
| SCHEMBL10123505 | 0.80 | HTT (0.64) | LMNAGAAMAPTHTT | |
| SCHEMBL10123513 | 0.80 | MAPT (0.64) | LMNAGAAMAPTHTT | |
| SCHEMBL10123581 | 0.80 | MAPT (0.59) | LMNAGAAMAPTHTT | |
| SCHEMBL13993357 | 0.79 | MAPT (0.62) | LMNAGAAMAPTHTT | |
| SCHEMBL10123372 | 0.79 | GAA (0.62) | LMNAGAAMAPTHTT | |
| SCHEMBL10123537 | 0.78 | GAA (0.61) | LMNAGAAMAPTHTT | |
| SCHEMBL10123582 | 0.77 | MAPT (0.59) | LMNAGAAMAPTHTTCA2 | |
| SCHEMBL10123376 | 0.77 | PDK1 (0.60) | LMNAGAAMAPTHTT | |
| SCHEMBL10123512 | 0.77 | ABCC9 (0.60) | GAAMAPTCA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060820-A1 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2012-05-10 | — | — | WO | disclosed |