Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.62 |
| ▸ | CA2 | P00918 | 16/20 | 0.62 |
| ▸ | CA9 | Q16790 | 13/20 | 0.62 |
| ▸ | CA12 | O43570 | 12/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL420788 | 0.95 | CA1 (0.64) | CA1CA2CA9CA12MAPT | |
| SCHEMBL10123512 | 0.84 | ABCC9 (0.60) | CA1CA2CA9CA12MAPT | |
| SCHEMBL5556342 | 0.83 | HTT (0.60) | CA1CA2CA9CA12MAPT | |
| SCHEMBL10123543 | 0.80 | MEN1 (0.59) | MAPTMEN1HTTKMT2A | |
| SCHEMBL10123510 | 0.80 | KMT2A (0.59) | MAPTMEN1HTTKMT2A | |
| SCHEMBL13993503 | 0.79 | KMT2A (0.62) | CA1CA2CA9CA12MAPT | |
| SCHEMBL420453 | 0.79 | MAPT (0.66) | CA1CA2CA9CA12MAPT | |
| SCHEMBL10123470 | 0.78 | MAPT (0.64) | MAPTMEN1HTTKMT2A | |
| SCHEMBL10123473 | 0.77 | PDK1 (0.62) | MAPTMEN1HTTKMT2A | |
| SCHEMBL14289838 | 0.77 | CA1 (0.74) | CA1CA2CA9CA12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060820-A1 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2012-05-10 | — | — | WO | disclosed |