SCHEMBL10123653

SCHEMBL10123653

C(=C/c1ccc(N(c2cccc(-c3ccccc3)c2)c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1)\c1ccc(N(c2cccc(-c3ccccc3)c2)c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.43
KDM4E B2RXH2 3/20 0.43
ATM Q13315 2/20 0.43
APP P05067 1/20 0.36
TSPO P30536 1/20 0.35
KMT2A Q03164 5/20 0.34
MEN1 O00255 4/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
USP2 O75604 2/20 0.34
MAPK1 P28482 1/20 0.34
CTNNB1 P35222 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
HDAC4 P56524 1/20 0.33
IL1R1 P14778 1/20 0.33
HTT P42858 2/20 0.32
CHEK1 O14757 2/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10123603 0.99 L3MBTL1 (0.42) L3MBTL1KDM4EATMAPPTSPO
SCHEMBL10123662 0.95 KDM4E (0.40) L3MBTL1KDM4EATMAPPTSPO
SCHEMBL10123613 0.94 L3MBTL1 (0.39) L3MBTL1KDM4EATMAPPTSPO
SCHEMBL10123655 0.94 L3MBTL1 (0.46) L3MBTL1KDM4EATMAPPTSPO
SCHEMBL10123794 0.94 L3MBTL1 (0.42) L3MBTL1KDM4EATMAPPTSPO
SCHEMBL10123604 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMAPPTSPO
SCHEMBL10123722 0.93 ATM (0.41) L3MBTL1KDM4EATMAPPTSPO
SCHEMBL10123661 0.93 ATM (0.41) L3MBTL1KDM4EATMAPPTSPO
SCHEMBL36256 0.93 KDM4E (0.50) L3MBTL1KDM4EATMAPPKMT2A
SCHEMBL36257 0.93 KDM4E (0.50) L3MBTL1KDM4EATMAPPKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
EP-1931634-B1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2011-11-09 EP disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-06-11 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
WO-2007043371-A1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-04-19 WO disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device NR0B1, NR2E3, NR0B2 L3MBTL1 2135/4885KDM4E 3101/4885ATM 1663/4885
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability NR0B1, TERB1, CYP1B1 L3MBTL1 1872/4885KDM4E 1410/4885ATM 1342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.