SCHEMBL10124152

SCHEMBL10124152

CNC(=O)c1cc(C(C)=O)cc(C)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MALT1 Q9UDY8 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124176 0.94 SLC2A1 (0.33) DHODHALDH1A1SMN1; SMN2
SCHEMBL10124122 0.93 DHODH (0.34) DHODHALDH1A1SMN1; SMN2MALT1
SCHEMBL10124116 0.93 NPC1 (0.32) DHODHALDH1A1SMN1; SMN2
SCHEMBL10124212 0.93 SLC2A1 (0.33) DHODHALDH1A1SMN1; SMN2HDAC6
SCHEMBL10124150 0.93 SLC16A3 (0.33) DHODHALDH1A1SMN1; SMN2
SCHEMBL19465207 0.93 SLC2A1 (0.33) DHODHALDH1A1SMN1; SMN2
SCHEMBL10151096 0.92 DHODH (0.33) DHODHALDH1A1SMN1; SMN2MALT1HDAC6
SCHEMBL685542 0.92 DHODH (0.33) DHODHALDH1A1SMN1; SMN2MALT1
SCHEMBL10072947 0.92 DHODH (0.33) DHODHALDH1A1SMN1; SMN2MALT1
SCHEMBL10124154 0.91 CRHR1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790202-B2 Anthranilamide derivatives as pesticides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-10-17 US disclosed
US-9790202-B2 Anthranilamide derivatives as pesticides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-10-17 US disclosed
US-20120010250-A1 Anthranilamide derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed
US-20120010250-A1 Anthranilamide derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010250-A1 Anthranilamide derivatives as pesticides ANTXR2, NQO2, AADAC DHODH 1510/4885ALDH1A1 1163/4885SMN1; SMN2 4194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.