SCHEMBL10124191

SCHEMBL10124191

Cc1cc(C(N)=O)cc(C(N)=O)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 5/20 0.34
SLC2A3 P11169 5/20 0.34
SLC2A4 P14672 5/20 0.34
SLC2A2 P11168 2/20 0.34
DHODH Q02127 3/20 0.33
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NTRK1 P04629 4/20 0.31
F10 P00742 1/20 0.31
GRM4 Q14833 1/20 0.31
MALT1 Q9UDY8 2/20 0.31
KLKB1 P03952 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124176 0.95 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL10124138 0.94 DHODH (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL10124179 0.94 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL31060080 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL11928375 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL685546 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL10124186 0.93 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13084942 0.93 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085036 0.92 DHODH (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085042 0.92 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790202-B2 Anthranilamide derivatives as pesticides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-10-17 US disclosed
US-9790202-B2 Anthranilamide derivatives as pesticides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-10-17 US disclosed
US-20120010250-A1 Anthranilamide derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed
US-20120010250-A1 Anthranilamide derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010250-A1 Anthranilamide derivatives as pesticides ANTXR2, NQO2, AADAC SLC2A1 4752/4885SLC2A3 4671/4885SLC2A4 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.