SCHEMBL13084942

SCHEMBL13084942

Cc1cc(F)cc(C(N)=O)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 11/20 0.34
SLC2A3 P11169 11/20 0.34
SLC2A4 P14672 11/20 0.34
SLC2A2 P11168 5/20 0.34
DHODH Q02127 3/20 0.33
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
P2RX7 Q99572 1/20 0.32
PARP1 P09874 1/20 0.32
CHRNA7 P36544 1/20 0.32
GPR52 Q9Y2T5 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
HRH2 P25021 1/20 0.31
HRH1 P35367 1/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15489000 0.94 DHODH (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL11928375 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL685546 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL31060080 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL10072947 0.93 DHODH (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL10124191 0.93 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085036 0.92 DHODH (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085042 0.92 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL15488992 0.92 DHODH (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085082 0.92 DHODH (0.32) DHODHALDH1A1SMN1; SMN2P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC2A1 2324/4885SLC2A3 2023/4885SLC2A4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.