SCHEMBL31060080

SCHEMBL31060080

Cc1cc(Cl)cc(C(N)=O)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 5/20 0.35
SLC2A3 P11169 5/20 0.35
SLC2A4 P14672 5/20 0.35
SLC2A2 P11168 2/20 0.35
DHODH Q02127 3/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
NTRK1 P04629 3/20 0.31
MALT1 Q9UDY8 3/20 0.31
ADRA1D P25100 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
F10 P00742 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL685546 1.00 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL686615 0.94 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085019 0.94 DHODH (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL11928375 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085230 0.94 P2RX7 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2NTRK1
SCHEMBL10124191 0.94 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13084942 0.94 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL15488985 0.93 DHODH (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13084948 0.93 DHODH (0.32) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL11928476 0.93 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4SLC2A2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 SLC2A1 395/4885SLC2A3 825/4885SLC2A4 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.