Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10324049 | 0.79 | SMPD1 (0.46) | SMPD1LAP3 | |
| SCHEMBL2048208 | 0.78 | SMPD1 (0.48) | SMPD1MEN1KMT2ALAP3LPAR2 | |
| SCHEMBL28192080 | 0.77 | LPAR3 (0.42) | SMPD1LPAR2LPAR3 | |
| SCHEMBL27823317 | 0.77 | SMPD1 (0.56) | SMPD1LAP3LPAR2LPAR3 | |
| SCHEMBL5303308 | 0.77 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL1012660 | 0.77 | SMPD1 (0.32) | SMPD1LPAR2LPAR3 | |
| SCHEMBL4896522 | 0.76 | SMPD1 (0.34) | SMPD1LPAR2LPAR3 | |
| SCHEMBL2048023 | 0.75 | SMPD1 (0.50) | SMPD1LAP3LPAR2LPAR3 | |
| Phosphoric Acid SCHEMBL1012536 | 0.73 | TSHR (0.36) | MEN1KMT2ALAP3 | |
| SCHEMBL18048851 | 0.73 | SMPD1 (0.30) | SMPD1LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842559-A2 | Compounds, compositions and methods for the treatment of viral infections and other medical disorders | Chimerix, Inc. (US) | 2015-03-04 | — | — | EP | disclosed |
| US-20110015149-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS | CHIMERIX, INC. | 2011-01-20 | — | — | US | disclosed |
| US-7517858-B1 | Prodrugs of pharmaceuticals with improved bioavailability | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-14 | — | — | US | disclosed |
| EP-1865967-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS | Chimerix, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006110656-A9 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS | CHIMERIX INC (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20070003608-A1 | Compounds, compositions and methods for the treatment of viral infections and other medical disorders | CHIMERIX, INC. | 2007-01-04 | — | — | US | disclosed |
| WO-2006110656-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS | CHIMERIX, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| EP-0837630-A4 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | UNIV CALIFORNIA (US) | 1998-11-25 | — | — | EP | disclosed |
| EP-0837630-A1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1996039831-A1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015149-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS | ACE, CYP27A1, LIPC | SMPD1 57/4885MEN1 3708/4885KMT2A 1424/4885 |
| US-20070003608-A1 | Compounds, compositions and methods for the treatment of viral infections and other medical disorders | ACE, CYP27A1, LIPC | SMPD1 57/4885MEN1 3708/4885KMT2A 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.