Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178236 | 0.84 | ACP1 (0.38) | LMNASCN9AULK1CA1CA2 | |
| SCHEMBL17689338 | 0.84 | HDAC3 (0.38) | LMNASCN9AULK1ALDH1A1MEN1 | |
| SCHEMBL10127277 | 0.84 | MAOB (0.39) | LMNACA1CA2MRGPRX4ALDH1A1 | |
| SCHEMBL21524633 | 0.84 | CYP2D6 (0.41) | LMNASCN9AULK1CA1CA2 | |
| SCHEMBL25756627 | 0.81 | TP53 (0.35) | LMNACA1CA2MRGPRX4ALDH1A1 | |
| SCHEMBL22328739 | 0.80 | HPGD (0.37) | LMNASCN9AULK1ALDH1A1HPGD | |
| SCHEMBL178271 | 0.80 | LMNA (0.57) | LMNACA1CA2ALDH1A1RCE1 | |
| SCHEMBL178133 | 0.77 | CYP2D6 (0.44) | SCN9AULK1CA1CA2ALDH1A1 | |
| SCHEMBL10127147 | 0.77 | EGLN1 (0.43) | LMNACA1CA2 | |
| SCHEMBL15580854 | 0.76 | TP53 (0.37) | LMNAALDH1A1KMT2AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027623-A2 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027618-A2 | FUNCTIONALIZED CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |