Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689338 | 0.84 | HDAC3 (0.38) | TLR7LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22259933 | 0.83 | KDM4E (0.40) | CA2POLBTLR7KDM4EMAOB | |
| SCHEMBL10127277 | 0.81 | MAOB (0.39) | CA1CA2MRGPRX4LMNAKDM4E | |
| SCHEMBL10126516 | 0.81 | LMNA (0.36) | CA1CA2MRGPRX4TLR7LMNA | |
| SCHEMBL178236 | 0.81 | ACP1 (0.38) | CA1CA2MRGPRX4LMNAL3MBTL1 | |
| SCHEMBL21524633 | 0.81 | CYP2D6 (0.41) | CA1CA2MRGPRX4TLR7LMNA | |
| SCHEMBL22328739 | 0.81 | HPGD (0.37) | POLBLMNAMAPK8ALDH1A1HPGD | |
| SCHEMBL19976528 | 0.80 | PDE5A (0.42) | POLBLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15580854 | 0.79 | TP53 (0.37) | TP53POLBTLR7LMNAKDM4E | |
| SCHEMBL178271 | 0.78 | LMNA (0.57) | CA1CA2POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2850086-B1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2023-07-05 | — | — | EP | disclosed |