SCHEMBL10126573

SCHEMBL10126573

Cc1ccc2c(c1)C(CCCCCCC(=O)O)(CCCCCCC(=O)O)c1cc(C)ccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.45
TSHR P16473 2/20 0.44
GAA P10253 2/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PDK2 Q15119 2/20 0.38
F13A1 P00488 3/20 0.37
MAPT P10636 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19104605 1.00 APEX1 (0.45) APEX1TSHRGAAKMT2AMEN1
SCHEMBL10111020 0.94 GPR84 (0.46) APEX1TSHRKMT2AMEN1ALDH1A1
SCHEMBL14277908 0.87 APEX1 (0.59) APEX1TSHRGAAKMT2AMEN1
SCHEMBL19101541 0.87 GPR84 (0.38) APEX1TSHRKMT2AMEN1ALDH1A1
SCHEMBL10111022 0.85 GPR84 (0.36) APEX1TSHRKMT2AMEN1ALDH1A1
SCHEMBL22373070 0.83 APEX1 (0.54) APEX1TSHRGAAKMT2AMEN1
SCHEMBL12924928 0.82 APEX1 (0.42) APEX1TSHRGAAKMT2AMEN1
SCHEMBL19442933 0.79 CNR1 (0.40) KMT2AMEN1PDK2NFKB1
SCHEMBL26050718 0.79 CNR1 (0.40) KMT2AMEN1PDK2NFKB1
SCHEMBL21561551 0.78 APEX1 (0.39) APEX1TSHRKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF CDH1, EPCAM, CD4 APEX1 480/4885TSHR 3714/4885GAA 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.