SCHEMBL1012760

SCHEMBL1012760

CC(C)CC1=CC2CCC1C2

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6241014 0.77
SCHEMBL8505218 0.76 CYP19A1 (0.33) CYP19A1
SCHEMBL4652198 0.73
SCHEMBL12191959 0.73 CYP19A1 (0.31) CYP19A1
SCHEMBL3126659 0.72
SCHEMBL516934 0.72
SCHEMBL1978763 0.72 CYP19A1 (0.31) CYP19A1
SCHEMBL9352940 0.72
SCHEMBL9154625 0.72
SCHEMBL11448709 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1372844-B1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2011-01-05 EP claimed
US-6838489-B2 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor CYMETECH, LLC (US) 2005-01-04 US claimed
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor STERLING JA, L.C. 2003-07-31 US claimed
US-4614778-A ETHYLENE AND A 1,4,5,8-DIMETHANG-1,2,3,4,4A,5,8,8A-OCTAHYDRONAPHTHALENE MITSUI CHEMICALS, INC. (JP) 1986-09-30 US claimed
EP-1423195-B1 HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INST OF TECHN (US) 2016-03-02 EP disclosed
EP-2756112-A2 IMPROVED ELECTROLYTIC CELL COVERS COMPRISING A RESIN COMPOSITION POLYMERIZED WITH A GROUP 8 OLEFIN METATHESIS CATALYST Materia, Inc. (US) 2014-07-23 EP disclosed
WO-2013040519-A2 IMPROVED ELECTROLYTIC CELL COVERS COMPRISING A RESIN COMPOSITION POLYMERIZED WITH A GROUP 8 OLEFIN METATHESIS CATALYST MATERIA, INC. (US) 2013-03-21 WO disclosed
US-20120241250-A1 Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers EAKIN GEORGE R (US) 2012-09-27 US disclosed
EP-1372844-B1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2011-01-05 EP disclosed
EP-1372844-A4 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2005-10-12 EP disclosed
US-6936672-B2 Mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO., LTD. (JP) 2005-08-30 US disclosed
EP-1423195-A4 HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INST OF TECHN (US) 2005-06-29 EP disclosed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN disclosed
US-6169152-B1 COPOLYMER OF ETHYLENE AND A POLAR GROUP-CONTAINING CYCLIC OLEFIN COMPRISING ESTER- OR ANHYDRIDE MODIFIED NORBORNENE OR PERHYDRO-2,3-DIDEHYDRO-1,4:5,8-DIMETHANONAPHTHALENE MADE WITH CATALYST SUCH AS 1,5,9-TRIAZACYCLODODECANYLTITANIUM CHLORIDE JSR CORPORATION (JP) 2001-01-02 US disclosed
EP-0816387-A1 Olefin-polymerizing catalyst JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-01-07 EP disclosed
EP-0582355-B1 Random copolymer MITSUI PETROCHEMICAL IND (JP) 1996-05-22 EP disclosed
EP-0156464-B1 Random copolymer MITSUI PETROCHEMICAL IND (JP) 1996-05-22 EP disclosed
EP-0582355-A1 Random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-02-09 EP disclosed
US-4614778-A ETHYLENE AND A 1,4,5,8-DIMETHANG-1,2,3,4,4A,5,8,8A-OCTAHYDRONAPHTHALENE MITSUI CHEMICALS, INC. (JP) 1986-09-30 US disclosed
EP-0156464-A1 Random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor NQO1, NIT2, ALOX5 CYP19A1 226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.