⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978763 | 0.82 | CYP19A1 (0.31) | — | |
| SCHEMBL8505218 | 0.81 | CYP19A1 (0.33) | — | |
| SCHEMBL1978579 | 0.78 | — | — | |
| SCHEMBL3126659 | 0.77 | — | — | |
| SCHEMBL9154625 | 0.77 | — | — | |
| SCHEMBL9352940 | 0.77 | — | — | |
| SCHEMBL7195260 | 0.77 | — | — | |
| SCHEMBL16242856 | 0.75 | MAOA (0.32) | — | |
| SCHEMBL145955 | 0.74 | — | — | |
| SCHEMBL1955612 | 0.74 | CYP19A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535751-B2 | Asymmetrically substituted polyorganosiloxane derivatives | MOMENTIVE PERFORMANCE MATERIALS GMBH | 2022-12-27 | — | — | US | claimed |
| CN-108026279-B | Asymmetrically substituted polyorganosiloxane derivatives | 莫门蒂夫性能材料有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-108026372-B | Modified filler particles and silicone compositions containing the same | 莫门蒂夫性能材料有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-106496565-B | A kind of tackifier, preparation method and silicone rubber compound | 东莞市贝特利新材料有限公司 | 2019-08-30 | — | — | CN | claimed |
| US-20180371248-A1 | ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2018-12-27 | — | — | US | claimed |
| US-20180208718-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-07-26 | — | — | US | claimed |
| EP-3325557-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | Momentive Performance Materials GmbH (DE) | 2018-05-30 | — | — | EP | claimed |
| EP-3325540-A1 | ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES | Momentive Performance Materials GmbH (DE) | 2018-05-30 | — | — | EP | claimed |
| CN-108026372-A | Modified filler particles and the silicon composition comprising the particle | 莫门蒂夫性能材料有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-108026279-A | The poly organo alkane derivatives of Asymmetrical substitute | 莫门蒂夫性能材料有限公司 | 2018-05-11 | — | — | CN | claimed |
| US-7001590-B1 | Metathesis-curable composition | KERR CORPORATION (US) | 2006-02-21 | — | — | US | claimed |
| EP-1620477-A2 | METATHESIS-CURABLE COMPOSITION WITH A REACTION CONTROL AGENT | Kerr Corporation (US) | 2006-02-01 | — | — | EP | claimed |
| US-6844409-B2 | Composition curable by metathesis reaction | KERR CORPORATION (US) | 2005-01-18 | — | — | US | claimed |
| US-20040254320-A1 | Metathesis-curable composition with a reaction control agent | KERR CORPORATION | 2004-12-16 | — | — | US | claimed |
| WO-2004101685-A2 | METATHESIS-CURABLE COMPOSITION WITH A REACTION CONTROL AGENT | KERR CORPORATION (US) | 2004-11-25 | — | — | WO | claimed |
| US-20040225072-A1 | Method of curing composition by metathesis reaction using reaction control agent | KERR CORPORATION | 2004-11-11 | — | — | US | claimed |
| US-20040225073-A1 | Metathesis-curable composition with a reaction control agent | KERR CORPORATION | 2004-11-11 | — | — | US | claimed |
| US-6653365-B2 | Polymerizable resin, a filler system comprising polyhedral polysilsesquioxane fillers, and a curing system; useful as crown and bridge materials, reconstructive or restorative materials | PENTRON CLINICAL TECHNOLOGIES, LLC | 2003-11-25 | — | — | US | claimed |
| US-20030212233-A1 | Composition curable by metathesis reaction | KERR CORPORATION | 2003-11-13 | — | — | US | claimed |
| US-20020198282-A1 | Dental composite materials and method of manufacture thereof | PENTRON CORPORATION | 2002-12-26 | — | — | US | claimed |