Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128271 | 0.80 | TSHR (0.46) | TSHRTP53TDP1PPARDALDH1A1 | |
| SCHEMBL10128548 | 0.77 | PPARD (0.39) | TSHRTP53TDP1PPARDALDH1A1 | |
| SCHEMBL10426582 | 0.77 | TSHR (0.48) | TSHRTP53TDP1PPARDACHE | |
| SCHEMBL4434268 | 0.77 | TSHR (0.48) | TSHRTP53TDP1PPARDACHE | |
| SCHEMBL10128728 | 0.74 | TSHR (0.40) | TSHRTP53TDP1PPARD | |
| SCHEMBL13657439 | 0.74 | TSHR (0.50) | TSHRTP53TDP1PPARDALDH1A1 | |
| SCHEMBL9115350 | 0.74 | TSHR (0.50) | TSHRTP53TDP1PPARDALDH1A1 | |
| SCHEMBL25285395 | 0.73 | TSHR (0.43) | TSHRTP53TDP1PPARDACHE | |
| SCHEMBL5595512 | 0.73 | TSHR (0.43) | TSHRTP53TDP1PPARDACHE | |
| SCHEMBL4757795 | 0.73 | TSHR (0.43) | TSHRTP53TDP1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | ETH ZURICH (CH) | 2020-06-02 | — | — | US | disclosed |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2019-02-07 | — | — | US | disclosed |
| EP-2057173-B1 | AMIDES AS SPHINGOMYELINE INHIBITORS | NOVARTIS AG (CH) | 2014-02-26 | — | — | EP | disclosed |
| US-8119617-B2 | aSMase inhibitors | NOVARTIS AG (CH) | 2012-02-21 | — | — | US | disclosed |
| US-20100022482-A1 | aSMase inhibitors | NOVARTIS AG (CH) | 2010-01-28 | — | — | US | disclosed |
| US-20100022482-A1 | aSMase inhibitors | NOVARTIS AG (CH) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022482-A1 | aSMase inhibitors | SMPD1, SMPD3, SMPD2 | TSHR 2541/4885TP53 4791/4885TDP1 1139/4885 |
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | TPO, FANCF, FANCI | TSHR 14/4885TP53 850/4885TDP1 3789/4885 |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | TPO, FANCF, FANCI | TSHR 14/4885TP53 850/4885TDP1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.