Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263167 | 0.85 | TSHR (0.43) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL25463304 | 0.79 | TSHR (0.39) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL3146731 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL9614639 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARDNPSR1 | |
| SCHEMBL10426582 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARD | |
| SCHEMBL4434268 | 0.79 | TSHR (0.48) | TSHRTP53TDP1PPARD | |
| SCHEMBL10128271 | 0.77 | TSHR (0.46) | TSHRTP53TDP1PPARD | |
| SCHEMBL19772489 | 0.76 | MEN1 (0.36) | TSHRTP53TDP1 | |
| SCHEMBL1076969 | 0.75 | TSHR (0.43) | TSHRTP53TDP1PPARD | |
| SCHEMBL5595512 | 0.75 | TSHR (0.43) | TSHRTP53TDP1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435841-B2 | Preparation of halohydrocarbyl phosphonic acid diesters | RHODIA INC. (US) | 2008-10-14 | — | — | US | disclosed |
| WO-2005086961-A2 | IMPROVED PREPARATION OF HALOHYDROCCARBYL PHOSPHONIC ACID DIESTRES | RHODIA INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050203306-A1 | Preparation of halohydrocarbyl phosphonic acid diesters | RHODIA OPERATIONS (FR) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203306-A1 | Preparation of halohydrocarbyl phosphonic acid diesters | HDHD5, PHYKPL, HPD | TSHR 2066/4885TP53 3640/4885TDP1 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.