Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14773229 | 0.85 | POLB (0.40) | PTPN1KDM4EMEN1MAPTHTT | |
| SCHEMBL10111632 | 0.83 | PTPN1 (0.37) | PTPN1 | |
| SCHEMBL14453264 | 0.76 | KDM4E (0.42) | KDM4EMEN1MAPTHTTKMT2A | |
| SCHEMBL13171951 | 0.75 | PTPN1 (0.40) | PTPN1PARK7RXRA | |
| SCHEMBL19063564 | 0.73 | PTPN1 (0.67) | PTPN1MEN1MAPTHTTKMT2A | |
| SCHEMBL14769839 | 0.72 | ALDH1A1 (0.47) | KDM4EMEN1MAPTHTTKMT2A | |
| SCHEMBL14773230 | 0.71 | MEN1 (0.41) | KDM4EMEN1MAPTHTTKMT2A | |
| SCHEMBL19052122 | 0.71 | PTPN1 (0.61) | PTPN1MEN1MAPTHTTKMT2A | |
| SCHEMBL13222394 | 0.71 | PTPN1 (0.45) | PTPN1KDM4EMEN1MAPTHTT | |
| SCHEMBL7704453 | 0.70 | MLNR (0.40) | PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| WO-2012027623-A2 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | PTPN1 3264/4885PARK7 196/4885KDM4E 2687/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | PTPN1 3264/4885PARK7 196/4885KDM4E 2687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.