SCHEMBL10128495

SCHEMBL10128495

c1ccc(-c2cc(-c3ccccc3)n(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ATM Q13315 1/20 0.53
HPGD P15428 1/20 0.44
KMT2A Q03164 3/20 0.41
HDAC4 P56524 1/20 0.40
IL1R1 P14778 1/20 0.38
HTR7 P34969 1/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
COMT P21964 1/20 0.37
RAC2 P15153 1/20 0.36
RAC3 P60763 1/20 0.36
CDC42 P60953 1/20 0.36
RAC1 P63000 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PTPN1 P18031 2/20 0.35
GPR3 P46089 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29518533 0.80 L3MBTL1 (0.74) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL29362803 0.80 L3MBTL1 (0.74) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL4794282 0.80 COMT (0.50) L3MBTL1KDM4EATMHPGDKMT2A
SCHEMBL560312 0.80 L3MBTL1 (0.74) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL15213597 0.80 L3MBTL1 (0.74) L3MBTL1KDM4EATMKMT2AHDAC4
Biphenyl SCHEMBL28096944 0.80 L3MBTL1 (0.74) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL14160396 0.80 L3MBTL1 (0.74) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL24581894 0.79 L3MBTL1 (0.65) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL9968550 0.79 L3MBTL1 (0.65) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL9968531 0.79 L3MBTL1 (0.65) L3MBTL1KDM4EATMKMT2AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207526-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-06-26 US disclosed
US-8207526-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-06-26 US disclosed
US-20100044689-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-02-25 US disclosed
US-20100044689-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-02-25 US disclosed