Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128495 | 0.80 | L3MBTL1 (0.53) | COMTKMT2AGLO1L3MBTL1HSP90AA1 | |
| SCHEMBL17916163 | 0.80 | ALDH1A1 (0.52) | COMTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL438086 | 0.79 | ALDH1A1 (0.57) | COMTKMT2AL3MBTL1ALDH1A1PKM | |
| SCHEMBL18947280 | 0.78 | COMT (0.53) | COMTKMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL9558331 | 0.78 | TET2 (0.40) | COMTRAB9ANPC1HSP90AA1ALDH1A1 | |
| SCHEMBL15089192 | 0.73 | GLO1 (0.42) | COMTKMT2AGLO1L3MBTL1RAB9A | |
| SCHEMBL10513428 | 0.71 | ALDH1A1 (0.50) | COMTKMT2AGLO1L3MBTL1RAB9A | |
| SCHEMBL347805 | 0.70 | PCSK9 (0.53) | COMTKMT2ARAB9ANPC1ALDH1A1 | |
| Biphenyl SCHEMBL21647236 | 0.67 | ALDH1A1 (0.90) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| Biphenyl SCHEMBL547965 | 0.67 | ALDH1A1 (0.90) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889617-A1 | Triphenyl modified 5-membered heterocycles and their use as anticancer and antiflammatory agents | Freie Universität Berlin (DE) | 2008-02-20 | — | — | EP | claimed |
| CN-114078444-B | Pixel circuit and display device using the same | 乐金显示有限公司 | 2024-02-13 | — | — | CN | disclosed |
| US-10065976-B2 | Titanium (IV) compounds and methods of forming heterocyclic compounds using same | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-09-04 | — | — | US | disclosed |
| US-20170158718-A9 | TITANIUM (IV) COMPOUNDS AND METHODS OF FORMING HETEROCYCLIC COMPOUNDS USING SAME | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-06-08 | — | — | US | disclosed |
| US-20170158718-A9 | TITANIUM (IV) COMPOUNDS AND METHODS OF FORMING HETEROCYCLIC COMPOUNDS USING SAME | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-06-08 | — | — | US | disclosed |
| US-20160200746-A1 | TITANIUM (IV) COMPOUNDS AND METHODS OF FORMING HETEROCYCLIC COMPOUNDS USING SAME | UNIV MINNESOTA (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160200746-A1 | TITANIUM (IV) COMPOUNDS AND METHODS OF FORMING HETEROCYCLIC COMPOUNDS USING SAME | UNIV MINNESOTA (US) | 2016-07-14 | — | — | US | disclosed |
| EP-1889617-A1 | Triphenyl modified 5-membered heterocycles and their use as anticancer and antiflammatory agents | Freie Universität Berlin (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2008006626-A1 | TRIPHENYL MODIFIED 5-MEMBERED HETEROCYCLES AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | FREIE UNIVERSITÄT BERLIN (DE) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200746-A1 | TITANIUM (IV) COMPOUNDS AND METHODS OF FORMING HETEROCYCLIC COMPOUNDS USING SAME | TERT, PIK3C3, TPI1 | COMT 4/4885KMT2A 234/4885GLO1 600/4885 |
| US-20170158718-A9 | TITANIUM (IV) COMPOUNDS AND METHODS OF FORMING HETEROCYCLIC COMPOUNDS USING SAME | TERT, PIK3C3, TPI1 | COMT 4/4885KMT2A 234/4885GLO1 600/4885 |
| US-10065976-B2 | Titanium (IV) compounds and methods of forming heterocyclic compounds using same | TERT, PIK3C3, TPI1 | COMT 4/4885KMT2A 234/4885GLO1 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.