Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.51 |
| ▸ | RBP4 | P02753 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17515577 | 1.00 | BPTF (0.51) | BPTFRBP4KMT2ACHRNA7CHRNB2 | |
| Hydrochloric Acid SCHEMBL17502965 | 0.98 | BPTF (0.50) | BPTFRBP4KMT2ACHRNA7CHRNB2 | |
| Hydrochloric Acid SCHEMBL1394230 | 0.98 | BPTF (0.50) | BPTFRBP4KMT2ACHRNA7CHRNB2 | |
| SCHEMBL19614564 | 0.79 | NOTUM (0.48) | RBP4KMT2AAKR1C3HSD11B1 | |
| SCHEMBL23744698 | 0.78 | RBP4 (0.44) | RBP4KMT2AAKR1C3HSD11B1 | |
| SCHEMBL30345809 | 0.78 | RBP4 (0.44) | RBP4KMT2AAKR1C3HSD11B1 | |
| SCHEMBL30345707 | 0.78 | RBP4 (0.44) | RBP4KMT2AAKR1C3HSD11B1 | |
| SCHEMBL23744701 | 0.78 | RBP4 (0.44) | RBP4KMT2AAKR1C3HSD11B1 | |
| SCHEMBL20533587 | 0.78 | RBP4 (0.50) | RBP4KMT2AAKR1C3HSD11B1 | |
| SCHEMBL22720929 | 0.77 | BPTF (0.56) | BPTFKMT2ACHRNA7CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010186-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2012-01-12 | — | — | US | disclosed |
| WO-2010108268-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010186-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, FASN | BPTF 1712/4885RBP4 602/4885KMT2A 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.