Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14609981 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AHTR2CGAA | |
| SCHEMBL5118035 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AHTR2CGAA | |
| SCHEMBL1164489 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AHTR2CGAA | |
| SCHEMBL26113894 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AHTR2CGAA | |
| SCHEMBL5122959 | 0.69 | HTR2C (0.45) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL204928 | 0.69 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AHTR2CGAA | |
| SCHEMBL26115372 | 0.69 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AHTR2CGAA | |
| SCHEMBL5122115 | 0.69 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AHTR2CGAA | |
| SCHEMBL7243880 | 0.68 | AGTR2 (0.53) | SMN1; SMN2NPC1RAB9AHTR2CGAA | |
| SCHEMBL5127061 | 0.68 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AHTR2CGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |