⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387129 | 1.00 | — | — | |
| SCHEMBL8997 | 1.00 | — | — | |
| Pyrrole SCHEMBL28453531 | 0.87 | RYR2 (0.48) | — | |
| SCHEMBL1267700 | 0.85 | RYR2 (0.50) | — | |
| SCHEMBL30118876 | 0.85 | RYR2 (0.50) | — | |
| SCHEMBL130168 | 0.85 | RYR2 (0.50) | — | |
| SCHEMBL542070 | 0.83 | TSHR (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL4616136 | 0.81 | TSHR (0.50) | — | |
| SCHEMBL7065387 | 0.81 | TSHR (0.50) | — | |
| SCHEMBL7062470 | 0.81 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | claimed |
| US-6369074-B1 | Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists | PFIZER INC. | 2002-04-09 | — | — | US | claimed |
| US-20240199656-A1 | BORON NEUTRON CAPTURE THERAPY (BNCT) PROBE | THE UNIVERSITY OF TOKYO (JP) | 2024-06-20 | — | — | US | disclosed |
| WO-2023219136-A1 | FLUORESCENT PROBE FOR DETECTING PEPTIDE-LINKED HYDROLASE | 国立大学法人 東京大学 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023167282-A1 | O-FUNCTION-TYPE ACTIVATABLE RAMAN PROBE | 国立大学法人 東京大学 | 2023-09-07 | — | — | WO | disclosed |
| WO-2023145967-A1 | PROBE FOR NUCLEAR MEDICAL TESTING | 国立大学法人 東京大学 | 2023-08-03 | — | — | WO | disclosed |
| WO-2023100942-A1 | COMPOUND FOR PHOTOOXYGENATION CATALYST AND MEDICINAL COMPOSITION CONTAINING SAME | 国立大学法人 東京大学 | 2023-06-08 | — | — | WO | disclosed |
| US-11655269-B2 | Prodrug-type anticancer agent using cancer-specific enzymatic activity | THE UNIVERSITY OF TOKYO (JP) | 2023-05-23 | — | — | US | disclosed |
| US-20230103890-A1 | Photooxygenation Catalyst Compound and Medicine Comprising Same | THE UNIVERSITY OF TOKYO (JP) | 2023-04-06 | — | — | US | disclosed |
| US-11591359-B2 | Enzyme-specific intracellularly-retained red fluorescent probe | THE UNIVERSITY OF TOKYO (JP) | 2023-02-28 | — | — | US | disclosed |
| WO-1994013663-A1 | AMINOMETHYLENE SUBSTITUTED NON-AROMATIC HETEROCYCLES AND USE AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1994-06-23 | — | — | WO | disclosed |
| EP-0602586-A2 | Stable pharmaceutical composition of fumagillol derivatives | Takeda Chemical Industries, Ltd. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0555693-A1 | Method of producing highly watersoluble cyclodextrin complex | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5202352-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-5196406-A | Antitumor, antiinflammatory | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-23 | — | — | US | disclosed |
| US-5180735-A | Antitumor agents, angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0519428-A2 | Cyclodextrin composition | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0470569-A1 | Intravascular embolizing agent containing angiogenesis inhibiting substance | Takeda Chemical Industries, Ltd. (JP) | 1992-02-12 | — | — | EP | disclosed |
| EP-0461427-A2 | Cyclodextrin complex | Takeda Chemical Industries, Ltd. (JP) | 1991-12-18 | — | — | EP | disclosed |