SCHEMBL8997

SCHEMBL8997

c1ccc2c(c1)CCS2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012871 1.00
SCHEMBL29387129 1.00
Pyrrole SCHEMBL28453531 0.87 RYR2 (0.48)
SCHEMBL1267700 0.85 RYR2 (0.50)
SCHEMBL30118876 0.85 RYR2 (0.50)
SCHEMBL130168 0.85 RYR2 (0.50)
SCHEMBL542070 0.83 TSHR (0.52)
Ammonia Solution, Strong SCHEMBL4616136 0.81 TSHR (0.50)
SCHEMBL7065387 0.81 TSHR (0.50)
SCHEMBL7062470 0.81 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7566 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
EP-4706820-A1 ENANTIOSELECTIVE C-H AMINATION WITH IRON PHTHALOCYANINE AND DIAMMONIUM TEMPLATE CATALYSTS The University Of Hong Kong (CN) 2026-03-11 EP claimed
EP-4188379-B1 POLYCYCLIC CAP-DEPENDENT ENDONUCLEASE INHIBITORS FOR TREATING OR PREVENTING INFLUENZA MERCK SHARP & DOHME LLC (US) 2026-02-25 EP claimed
US-20250376469-A1 INDOLIZINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-12-11 US claimed
US-20250376468-A1 PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-12-11 US claimed
US-20250376461-A1 INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-12-11 US claimed
US-20250352988-A1 ENANTIOSELECTIVE C-H AMINATION WITH IRON PHTHALOCYANINE AND DIAMMONIUM TEMPLATE CATALYSTS UNIV HONG KONG (CN) 2025-11-20 US claimed
US-20250353858-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-20 US claimed
CN-119998280-A Pyrazolo [1,5-a ] pyridine derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-05-13 CN claimed
CN-119955552-A Complexing agent for automatically purifying, wearing and repairing engine fuel system and increasing driving mileage 广东大发环保研究院有限公司 2025-05-09 CN claimed
EP-0745586-A1 Aryl(alkyl) propylamides, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1996-12-04 EP claimed
EP-0721938-A1 Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1996-07-17 EP claimed
US-5514289-A ALSO HIGH TEMPERATURE ANTICORROSION ADDITIVES; USED FOR LUBRICANTS OR FUELS; PREPARED BY REACTING ARYLTHIOL WITH EPOXIDE OR ALDEHYDE MOBIL OIL CORPORATION (US) 1996-05-07 US claimed
US-5180735-A Antitumor agents, angiogenesis inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-01-19 US claimed
EP-0281261-B1 3-AMINOMETHYL DERIVATIVES OF INDANE, INDOLINE AND DIHYDROBENZOFURANE AND DIHYDROBENZOTHIOPHENE H. LUNDBECK A/S (DK) 1992-05-06 EP claimed
EP-0117961-B1 HETEROCYCLIC DERIVATIVES SUBSTITUTED BY AN AMINO RADICAL, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Albert ROLLAND S.A. Société dite (FR) 1991-04-03 EP claimed
US-4916223-A ALPAH 2-ADRENOCEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1990-04-10 US claimed
US-4847254-A CNS affecting 5-oxy-3-aminomethyl-dihydro-benzofurans and benzothiophenes H. LUNDBECK A/S (DK) 1989-07-11 US claimed
EP-0281261-A2 3-Aminomethyl derivatives of indane, indoline and dihydrobenzofurane and dihydrobenzothiophene H. LUNDBECK A/S (DK) 1988-09-07 EP claimed
US-4588484-A Electrochemical reduction of 3-chlorobenzo[b]thiophenes ELI LILLY AND COMPANY (US) 1986-05-13 US claimed