SCHEMBL130168

SCHEMBL130168

c1ccc2c(c1)CCCS2

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RYR2 Q92736 6/20 0.50
HPGD P15428 3/20 0.48
TSHR P16473 1/20 0.48
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP2A6 P11509 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CES1 P23141 1/20 0.34
MAPT P10636 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1267700 1.00 RYR2 (0.50) RYR2HPGDTSHRNPSR1MEN1
SCHEMBL30118876 1.00 RYR2 (0.50) RYR2HPGDTSHRNPSR1MEN1
SCHEMBL542070 0.93 TSHR (0.52) RYR2HPGDTSHRNPSR1MEN1
Ammonia Solution, Strong SCHEMBL4616136 0.91 TSHR (0.50) RYR2HPGDTSHRNPSR1MEN1
SCHEMBL7065387 0.91 TSHR (0.50) RYR2HPGDTSHRNPSR1MEN1
SCHEMBL7062470 0.91 TSHR (0.50) RYR2HPGDTSHRNPSR1MEN1
SCHEMBL1012871 0.85
SCHEMBL29387129 0.85
SCHEMBL8997 0.85
SCHEMBL30388238 0.83 RYR2 (0.36) RYR2HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2396 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4188379-B1 POLYCYCLIC CAP-DEPENDENT ENDONUCLEASE INHIBITORS FOR TREATING OR PREVENTING INFLUENZA MERCK SHARP & DOHME LLC (US) 2026-02-25 EP claimed
EP-4658655-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP claimed
US-20250353858-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-20 US claimed
EP-4630406-A1 AMIDE COMPOUNDS AS ACTIVATORS OF THE POTASSIUM CHANNELS KV7.2/KV7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS ANGELINI PHARMA S.P.A. (IT) 2025-10-15 EP claimed
EP-4630404-A1 UREA COMPOUNDS AS ACTIVATORS OF POTASSIUM CHANNELS KV7.2/7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS ANGELINI PHARMA S.P.A. (IT) 2025-10-15 EP claimed
CN-119937241-A Resist composition and pattern forming method using the same 三星电子株式会社 2025-05-06 CN claimed
WO-2024160278-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO claimed
CN-114031603-B Thiochroman 4-ketone compound, preparation method thereof and UV (ultraviolet) photocuring combination system thereof 深圳市大衍创新材料科技有限公司 2024-07-19 CN claimed
WO-2024121048-A1 UREA COMPOUNDS AS ACTIVATORS OF POTASSIUM CHANNELS KV7.2/7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS ANGELINI PHARMA S.P.A. (IT) 2024-06-13 WO claimed
WO-2024121046-A1 AMIDE COMPOUNDS AS ACTIVATORS OF THE POTASSIUM CHANNELS KV7.2/KV7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS ANGELINI PHARMA S.P.A. (IT) 2024-06-13 WO claimed
EP-1019360-A1 $g(b)2-ADRENERGIC RECEPTOR AGONISTS Advanced Medicine, Inc. (US) 2000-07-19 EP claimed
WO-1999064035-A9 β2-ADRENERGIC RECEPTOR AGONISTS ADVANCED MEDICINE INC (US) 2000-07-06 WO claimed
WO-1999064034-A9 β2-ADRENERGIC RECEPTOR AGONISTS ADVANCED MEDICINE INC (US) 2000-06-29 WO claimed
EP-1003540-A1 $g(b)2-ADRENERGIC RECEPTOR AGONISTS Advanced Medicine, Inc. (US) 2000-05-31 EP claimed
WO-1999064031-A9 β2-ADRENERGIC RECEPTOR AGONISTS ADVANCED MEDICINE INC (US) 2000-05-04 WO claimed
US-6008402-A REACTING CYCLOHEXADIENECARBOXYLATE-4-ONE COMPOUND WITH A BETA MERCAPTOPROPIONIC ACID TO GIVE THIOENOL, CYCLODEHYDRATING THE THIOENOL AMERICAN CYANAMID COMPANY (US) 1999-12-28 US claimed
WO-1999064031-A1 β2-ADRENERGIC RECEPTOR AGONISTS ADVANCED MEDICINE, INC. (US) 1999-12-16 WO claimed
WO-1999064035-A1 β2-ADRENERGIC RECEPTOR AGONISTS ADVANCED MEDICINE, INC. (US) 1999-12-16 WO claimed
WO-1999064034-A1 β2-ADRENERGIC RECEPTOR AGONISTS ADVANCED MEDICINE, INC. (US) 1999-12-16 WO claimed
EP-0915092-A1 Process for the preparation of 6-(arylcarbonyl)-4-oximo-dihydrobenzothiopyran herbicides and intermediates useful therein American Cyanamid Company (US) 1999-05-12 EP claimed