SCHEMBL1012916

SCHEMBL1012916

CCC(=O)c1ccccc1NS(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.48
MAPT P10636 2/20 0.47
TP53 P04637 1/20 0.47
GLA P06280 1/20 0.47
CDK1 P06493 1/20 0.41
ALOX15 P16050 1/20 0.41
CYP1A2 P05177 1/20 0.41
ELANE P08246 1/20 0.41
PRTN3 P24158 1/20 0.41
KMT2A Q03164 1/20 0.40
HDAC1 Q13547 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9248108 0.94 TSHR (0.48) GAAMAPTTP53GLAALOX15
SCHEMBL8535695 0.88 GAA (0.51) GAAMAPTTP53GLACDK1
SCHEMBL8380205 0.88 GAA (0.51) GAAMAPTTP53GLACDK1
SCHEMBL7808045 0.88 GAA (0.47) GAAMAPTTP53GLACDK1
SCHEMBL7808085 0.87 GAA (0.50) GAAMAPTTP53GLACDK1
SCHEMBL29510603 0.86 GAA (0.47) GAAMAPTTP53GLACDK1
SCHEMBL53468 0.86 GAA (0.47) GAAMAPTTP53GLACDK1
SCHEMBL7813210 0.86 GAA (0.49) GAAMAPTTP53GLACDK1
SCHEMBL7801275 0.86 GAA (0.45) GAAMAPTTP53GLACDK1
SCHEMBL6812884 0.85 GAA (0.47) GAAMAPTTP53GLACDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0965265-B1 AHAS-inhibiting herbicide resistant wheat and method for selection thereof BASF SE (DE) 2011-01-05 EP disclosed
US-7034208-B1 Ahas inhibiting herbicide resistant wheat and method for selection thereof BASF AKTIENGELLSCHAFT (DE) 2006-04-25 US disclosed
US-6339184-B1 SCREENING FOR THE SELECTION OF MUTATIONS WHICH CONFER ACETOHYDROXYACID SYNTHASE RESISTANCE TO WHEAT BASF AKTIENGELLSCHAFT (DE) 2002-01-15 US disclosed
EP-0508161-B1 Use of AHAS inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID CO (US) 2000-05-10 EP disclosed
EP-0965265-A2 AHAS-inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID COMPANY (US) 1999-12-22 EP disclosed
EP-0508161-A1 AHAS inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID COMPANY (US) 1992-10-14 EP disclosed