SCHEMBL53468

SCHEMBL53468

COc1cc(OC)nc(NC(=O)NS(=O)(=O)Nc2ccccc2C(=O)C2CC2)n1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.47
MAPT P10636 2/20 0.43
TP53 P04637 1/20 0.43
GLA P06280 1/20 0.43
CDK1 P06493 1/20 0.41
CYP1A2 P05177 1/20 0.40
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 2/20 0.39
ALOX15 P16050 1/20 0.39
HDAC1 Q13547 1/20 0.37
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510603 1.00 GAA (0.47) GAAMAPTTP53GLACDK1
SCHEMBL6812884 0.99 GAA (0.47) GAAMAPTTP53GLACDK1
SCHEMBL8539345 0.89 GAA (0.45) GAAMAPTTP53GLACDK1
SCHEMBL6573975 0.88 GAA (0.54) GAAMAPTTP53GLACDK1
SCHEMBL8539307 0.88 GAA (0.44) GAAMAPTTP53GLACDK1
Ethoxysulfuron SCHEMBL6447158 0.87 MRGPRX1 (0.41) GAAMAPTTP53KMT2AMEN1
SCHEMBL8535695 0.87 GAA (0.51) GAAMAPTTP53GLACDK1
SCHEMBL8380205 0.87 GAA (0.51) GAAMAPTTP53GLACDK1
SCHEMBL7801293 0.87 PTK2 (0.48) GAAMAPTTP53GLAALDH1A1
SCHEMBL8538021 0.86 GAA (0.43) GAAMAPTTP53GLACDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16694 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122004216-A Herbicide composition containing cyclohexene diketone lactic acid oxime ether derivative and application thereof 郑州手性药物研究院有限公司 2026-05-12 CN claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
CN-121577800-A Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) 2026-02-27 CN claimed
EP-4677099-A2 HERBICIDE-RESISTANT GENES FOR MITOCHONDRIAL TRANSFORMATION Napigen, Inc. (US) 2026-01-14 EP claimed
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
US-20250318528-A1 HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-16 US claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-4601471-A1 SUBSTITUTED 5-MEMBERED RINGS AND THEIR USE AS PESTICIDES Corteva Agriscience LLC (US) 2025-08-20 EP claimed
EP-0682007-A1 Method for the preparation of 4-halo-2'-nitrobutyrophenone AMERICAN CYANAMID COMPANY (US) 1995-11-15 EP claimed
EP-0463287-B1 1-((O-(cyclopropylcarbonyl)phenyl)sulfamoyl)-3-(4,6-dimethoxy-2-pyrimidinyl)urea and method for the preparation thereof AMERICAN CYANAMID CO (US) 1995-09-20 EP claimed
EP-0672663-A1 Herbicidal tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1995-09-20 EP claimed
EP-0657099-A1 Herbicidal composition RHONE-POULENC AGROCHIMIE (FR) 1995-06-14 EP claimed
US-5407897-A Plant safening agents AMERICAN CYANAMID COMPANY (US) 1995-04-18 US claimed
EP-0613618-A1 Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds AMERICAN CYANAMID COMPANY (US) 1994-09-07 EP claimed
WO-1994013665-A1 CYCLIC AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDAL COMPOSITIONS CONTAINING THEM ISHIHARA SANGYO KAISHA LTD. (JP) 1994-06-23 WO claimed
US-5280007-A Using 1-(a,a-dimethylbenzyl)-3-p-tolyurea and s-(1-methyl-1-phenylethyl-1-piperidinecarbothioate AMERICAN CYANAMID COMPANY (US) 1994-01-18 US claimed
EP-0463287-A1 1-((O-(cyclopropylcarbonyl)phenyl)sulfamoyl)-3-(4,6-dimethoxy-2-pyrimidinyl)urea and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1992-01-02 EP claimed
US-5009699-A 1-{[O-(cyclopropylcarbonyl)phenyl]sulfamoyl}-3-(4,6-dimethoxy-2-pyrimidinyl)urea herbicidal composition and use AMERICAN CYANAMID COMPANY (US) 1991-04-23 US claimed