SCHEMBL8535695

SCHEMBL8535695

COC(=O)c1ccccc1NS(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
TSHR P16473 1/20 0.47
MAPT P10636 2/20 0.46
TP53 P04637 1/20 0.46
GLA P06280 1/20 0.46
CYP1A2 P05177 1/20 0.44
CDK1 P06493 1/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
MAPK1 P28482 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380205 0.91 GAA (0.51) GAATSHRMAPTTP53GLA
SCHEMBL7808085 0.90 GAA (0.50) GAAMAPTTP53GLACYP1A2
SCHEMBL7813210 0.89 GAA (0.49) GAATSHRMAPTTP53GLA
SCHEMBL116126 0.88 CDK1 (0.55) GAATSHRMAPTTP53GLA
SCHEMBL7808110 0.88 GAA (0.48) GAATSHRMAPTTP53GLA
SCHEMBL29878397 0.88 CDK1 (0.55) GAATSHRMAPTTP53GLA
SCHEMBL1012916 0.88 GAA (0.48) GAATSHRMAPTTP53GLA
SCHEMBL29510603 0.87 GAA (0.47) GAATSHRMAPTTP53GLA
SCHEMBL53468 0.87 GAA (0.47) GAATSHRMAPTTP53GLA
SCHEMBL6812884 0.86 GAA (0.47) GAATSHRMAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4515620-A PRE- AND POSTEMERGENCE HERBICIDES, PLANT GROWTH REGULATORS CIBA GEIGY CORPORATION (US) 1985-05-07 US claimed
EP-0770603-B1 Alkynylphenylaminosulfonyl ureas as herbicides ISAGRO RICERCA SRL (IT) 1998-09-16 EP disclosed
EP-0770603-A1 Alkynylphenylaminosulfonyl ureas as herbicides ISAGRO RICERCA S.r.l. (IT) 1997-05-02 EP disclosed
US-4515620-A PRE- AND POSTEMERGENCE HERBICIDES, PLANT GROWTH REGULATORS CIBA GEIGY CORPORATION (US) 1985-05-07 US disclosed