SCHEMBL10130435

SCHEMBL10130435

c1ccc2cc(-c3ccc(-c4c5ccccc5c(-c5ccc(-c6ccc7ccccc7c6)cc5)c5cc(-c6ccc(-c7cc8ccccc8c8c7oc7ccccc78)cc6)ccc45)cc3)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 6/20 0.40
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
PLA2G2A P14555 1/20 0.34
PLA2G4A P47712 1/20 0.34
KDM4E B2RXH2 3/20 0.34
RAB9A P51151 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
CDC14B O60729 2/20 0.33
CDC14A Q9UNH5 2/20 0.33
HSD17B1 P14061 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10130437 0.94 GPR84 (0.41) GPR84TDP1L3MBTL1CYP1A1ESR1
SCHEMBL10130436 0.94 GPR84 (0.41) GPR84TDP1L3MBTL1CYP1A1ESR1
SCHEMBL9951354 0.94 GPR84 (0.41) GPR84TDP1L3MBTL1CYP1A1ESR1
SCHEMBL10130410 0.91 GPR84 (0.41) GPR84TDP1L3MBTL1CYP1A1CYP1B1
SCHEMBL10130475 0.91 GPR84 (0.40) GPR84TDP1L3MBTL1CYP1A1CYP1B1
SCHEMBL10130395 0.89 PLA2G2A (0.39) GPR84TDP1L3MBTL1ESR1ESR2
SCHEMBL9952160 0.89 TDP1 (0.39) GPR84TDP1L3MBTL1CYP1A1CYP1B1
SCHEMBL10130439 0.88 GPR84 (0.39) GPR84TDP1L3MBTL1ESR1ESR2
SCHEMBL10130456 0.88 PLA2G2A (0.38) GPR84TDP1L3MBTL1ESR1ESR2
SCHEMBL18996163 0.88 PLA2G2A (0.38) GPR84TDP1L3MBTL1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material CYP1B1, CTNND1, CTNNB1 GPR84 3217/4885TDP1 2470/4885L3MBTL1 2056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.