SCHEMBL10130461

SCHEMBL10130461

c1cc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccccc23)cc(-c2cc3ccccc3c3c2oc2ccccc23)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.44
ALOX5 P09917 1/20 0.39
MIF P14174 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP1A1 P04798 2/20 0.36
CYP1A2 P05177 2/20 0.36
FYN P06241 1/20 0.36
MAPK3 P27361 1/20 0.36
AHR P35869 1/20 0.36
PAX8 Q06710 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
GSTP1 P09211 1/20 0.36
PRKDC P78527 1/20 0.35
CYP1B1 Q16678 1/20 0.35
RAB9A P51151 2/20 0.35
KDM4E B2RXH2 2/20 0.35
NPC1 O15118 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10130410 0.95 GPR84 (0.41) GPR84ALOX5MIFTDP1L3MBTL1
SCHEMBL10130475 0.95 GPR84 (0.40) GPR84ALOX5TDP1L3MBTL1CYP1A1
SCHEMBL10130465 0.92 ALOX5 (0.40) GPR84ALOX5TDP1L3MBTL1CYP1A1
SCHEMBL9950744 0.92 ALOX5 (0.39) GPR84ALOX5TDP1L3MBTL1CYP1A1
SCHEMBL19080001 0.91 GPR84 (0.43) GPR84ALOX5MIFCYP1A1CYP1A2
SCHEMBL20363670 0.91 GPR84 (0.44) GPR84ALOX5MIFTDP1L3MBTL1
SCHEMBL19076396 0.91 GPR84 (0.40) GPR84ALOX5MIFTDP1L3MBTL1
SCHEMBL17945083 0.90 GPR84 (0.39) GPR84ALOX5MIFTDP1L3MBTL1
SCHEMBL19079999 0.90 GPR84 (0.44) GPR84MIFTDP1CYP1A1CYP1A2
SCHEMBL10130421 0.90 GPR84 (0.40) GPR84ALOX5MIFTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material CYP1B1, CTNND1, CTNNB1 GPR84 3217/4885ALOX5 1628/4885MIF 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.