⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986149 | 0.78 | — | — | |
| SCHEMBL19227940 | 0.78 | TRPA1 (0.35) | — | |
| SCHEMBL5986146 | 0.78 | — | — | |
| SCHEMBL27578845 | 0.74 | — | — | |
| SCHEMBL24063606 | 0.73 | — | — | |
| SCHEMBL18889765 | 0.73 | — | — | |
| SCHEMBL20957493 | 0.73 | — | — | |
| SCHEMBL20957494 | 0.73 | — | — | |
| SCHEMBL11198080 | 0.73 | CES2 (0.40) | — | |
| SCHEMBL20942865 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820503-B1 | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them | PFIZER ITALIA SRL (IT) | 2012-02-22 | — | — | EP | disclosed |