Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.44 |
| ▸ | PDE5A | O76074 | 4/20 | 0.44 |
| ▸ | PDE1A | P54750 | 4/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.44 |
| ▸ | RAC1 | P63000 | 3/20 | 0.39 |
| ▸ | CDC42 | P60953 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284017 | 0.90 | RAC1 (0.47) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL10132392 | 0.85 | RAC1 (0.42) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL10132388 | 0.84 | RAC1 (0.43) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL10132442 | 0.84 | RAC1 (0.39) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL10132383 | 0.79 | RAC1 (0.49) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL13284355 | 0.79 | ALDH1A1 (0.64) | RAC1CDC42RAD52ALDH1A1BCHE | |
| SCHEMBL10132397 | 0.78 | RAC1 (0.43) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL13284016 | 0.77 | RAC1 (0.51) | RAC1CDC42RAD52ALDH1A1BCHE | |
| SCHEMBL10132447 | 0.73 | RAC1 (0.44) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL13284021 | 0.73 | RAC1 (0.51) | RAC1CDC42RAD52ALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | PDE4A 1628/4885PDE4B 1634/4885PDE4C 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.