Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | BAD | Q92934 | 3/20 | 0.55 |
| ▸ | RGS17 | Q9UGC6 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132452 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL10132455 | 0.84 | BAD (0.53) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL10132457 | 0.83 | BAD (0.52) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL10132463 | 0.83 | TDP1 (0.51) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL10132407 | 0.80 | BAD (0.65) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL13284359 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL10132460 | 0.79 | BAD (0.53) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL10132461 | 0.78 | MAPK1 (0.47) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL13284128 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL13284360 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | ALDH1A1 3095/4885MAPT 4875/4885HPGD 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.